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TitleBonelike/PLGA hybrid materials for bone regeneration: in vivo evaluation
Author(s)Oliveira, Joaquim M.
Lopes, M. A.
Kawai, T.
Ohtsuki, C.
Santos, J. D.
Afonso, A.
Histological studies
Hybrid materials
In vivo
Issue date2004
PublisherTrans Tech Publications
JournalMaterials Science Forum
Abstract(s)The biocompatibility and osteoconductive potential of Bonelike and Bonelike /PLGA hybrid materials were evaluated through subcutaneous and tibiae implantations for a 4 week period. Qualitative histology was performed to evaluate new bone formation and characterise bone-implant interface and results showed that Bonelike /PLGA hybrid materials promote extensive bone growth. After the 4 week implantation period, Bonelike resorption was recognized, which may be due to the presence of resorbable and -tricalcium phosphate phases.
TypeConference paper
AccessOpen access
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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