Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/16016

TitleMonocarboxylate transporters: new molecular targets for colorectal carcinoma
Author(s)Amorim, Ricardo
Martins, Sandra
Pereira, Helena Paula Fernandes
Pinheiro, Céline
Reis, R. L.
Longatto Filho, Adhemar
Preto, Ana
Baltazar, Fátima
Issue date2011
Abstract(s)[Excerpt] Colorectal carcinoma (CRC) is the second leading cause of cancer-related death in industrialized countries1. 5-Fluorouracil (5-FU) is one of the most efficient chemotherapeutic agents in the treatment of CRC although resistance to 5-FU treatment has been reported2. CRC relies mostly on glycolysis to meet their energetic demands and, as a consequence, CRC cells produce large amounts of lactate that must be extruded to the tumour microenvironment by lactate transporters, namely monocarboxylate transporters (MCTs). (...)
TypeAbstract
URIhttp://hdl.handle.net/1822/16016
Peer-Reviewedno
AccessRestricted access (UMinho)
Appears in Collections:DBio - Comunicações/Communications in Congresses

Files in This Item:
File Description SizeFormat 
Abstract México (FINAL).pdf
  Restricted access
Documento principal196,79 kBAdobe PDFView/Open    Request a copy!

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID