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TitleBiology of human hair: Know your hair to control it
Author(s)Araújo, Rita
Fernandes, Margarida M.
Paulo, Artur Cavaco
Gomes, Andreia
KeywordsFollicular morphogenesis
Hair follicle
Hair life cycle
Issue date2011
JournalAdvances in Biochemical Engineering Biotechnology
Abstract(s)Hair can be engineered at different levels—its structure and surface—through modification of its constituent molecules, in particular proteins, but also the hair follicle (HF) can be genetically altered, in particular with the advent of siRNA-based applications. General aspects of hair biology are reviewed, as well as the most recent contributions to understanding hair pigmentation and the regulation of hair development. Focus will also be placed on the techniques developed specifically for delivering compounds of varying chemical nature to the HF, indicating methods for genetic/biochemical modulation of HF components for the treatment of hair diseases. Finally, hair fiber structure and chemical characteristics will be discussed as targets for keratin surface functionalization.
TypeBook part
Publisher version
AccessOpen access
Appears in Collections:DBio - Artigos/Papers
DET/2C2T - Artigos em revistas internacionais com arbitragem científica

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