Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/14067
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Oliveira, Joaquim M. | - |
dc.contributor.author | Miyazaki, T. | - |
dc.contributor.author | Lopes, M. A. | - |
dc.contributor.author | Ohtsuki, C. | - |
dc.contributor.author | Santos, J. D. | - |
dc.date.accessioned | 2011-10-31T11:40:50Z | - |
dc.date.available | 2011-10-31T11:40:50Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0957-4530 | por |
dc.identifier.uri | https://hdl.handle.net/1822/14067 | - |
dc.description.abstract | Bonelike R /PLGA hybrid materials have been developed using γ -MPS as silane-coupling agent between the inorganic and organic phases for controlled drug delivery applications. Silanization showed to be more effective when cyclohexane was used as a non-polar solvent (nP method) due to a chemical interaction between Bonelike R and the silane film, while by using a 95/5 (V/V) methanol/water as a polar solvent (P method), a much thinner film was achieved. Functional groups of PLGA, such as the carbonyl group (C O), were identified using Raman and FTIR-ATR analysis and therefore these groups may be used to link therapeutic molecules. These novel hybrid materials prepared by combining silanization and post-hybridisation processes are expected to find use in medical applications of bone regeneration and as drug delivery carrier for therapeutic molecules. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.title | Bonelike/PLGA hybrid materials for bone regeneration : preparation route and physicochemical characterisation | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 253 | por |
oaire.citationEndPage | 259 | por |
oaire.citationTitle | Journal of Materials Science : Materials in Medicine | por |
oaire.citationVolume | 16 | por |
sdum.journal | Journal of Materials Science: Materials in Medicine | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |